Principal Investigator
宋肖炜
Xiaowei Song
Assistant Professor
自强不息，厚德载物
Welcome to Song Lab
A young laboratory at Tsinghua Shenzhen International Graduate School
Single-Cell MultiomicsMicrodroplet ReactorsBiomolecular CondensatesArtificial OrganellesBiomembrane InterfacesClinical Mass Spectrometry
RESEARCH
RESEARCH
TEAM
TEAM
PhD Students
范云凯
Yunkai Fan
2026级博士生
PhD Students
赵东阳
Dongyang Zhao
2027级博士生
Research Assistants
曾仙童
Xiantong Zeng
科研助理
Master Students
刘雨田
Yutian Liu
2025级硕士研究生
Master Students
伍秋徉
Qiuyang Wu
2025级硕士研究生
ABOUT SONG
ABOUT SONG
宋肖炜
Xiaowei Song
助理教授，博士生导师
Emailsongxw@sz.tsinghua.edu.cn
Office国际一期 A1801
Institute生物医药与健康工程研究院
Academic Profile
宋肖炜，清华大学深圳国际研究生院生物医药与健康工程研究院助理教授、博士生导师。2026年1月入职清华大学深圳国际研究生院。研究聚焦质谱分析、空间代谢组学、临床分子诊断、微液滴化学与生物分子凝聚体化学，致力于发展面向生命体系与临床样本的新型分子测量技术。
教育经历
2014.09 - 2017.07｜北京协和医学院 / 清华大学医学部｜药物分析专业，博士
2009.09 - 2012.07｜沈阳药科大学｜药物分析专业，硕士
2005.09 - 2009.07｜沈阳药科大学｜药学专业，学士
工作经历
2026.01 - 至今｜清华大学深圳国际研究生院｜助理教授，博士生导师
2023.12 - 2025.12｜Stanford University, Department of Chemistry｜Research Scientist
2020.01 - 2023.11｜Stanford University, Department of Chemistry｜Postdoctoral Researcher
2017.08 - 2019.12｜复旦大学化学流动站｜Postdoctoral Researcher
学术兼职
TMR Modern Herbal Medicine 编委
Journal of Analysis and Testing、Acta Materia Medica 与 Metabolites 青年编委
Metabolites 客座编辑
Proc. Natl. Acad. Sci.、Analytical Chemistry、Acta Pharmaceutica Sinica B、Chinese Chemical Letters、iScience 等期刊审稿人
研究方向
基于质量标签策略的单细胞多组学质谱流式表征技术
介入式微创采样与常压电离质谱技术及其在临床活检诊断中的应用
质谱成像与空间多组学方法及其在疾病诊断、药物研发中的应用
生物液滴、脂滴与凝聚体反应器，人工细胞器构建及功能分子合成
生物膜界面组成、结构与功能的质谱表征方法
PUBLICATIONS
PUBLICATIONS
2026
Biomolecular condensates mediate C-N bond formationSong X. et al.
Nature Chemical Biology · DOI 10.1038/s41589-026-02169-2
2026
Biomolecular Condensates Power Nitrogen Cycling via Concurrent Redox ActivitiesSong X. et al.
Journal of the American Chemical Society · DOI 10.1021/jacs.5c22593
2026
Dark Reactions in Microdroplets Explain Widespread Artifacts in Metabolomic ProfilingSong X. et al.
ACS Measurement Science Au · DOI 10.1021/acsmeasuresciau.5c00146
2026
Synthesizing Boron Nitride Quantum Dots in MicrodropletsSong X., Lyu L., Xu J., Li C., Basheer C., Zare R. N. et al.
Nano Letters · DOI 10.1021/acs.nanolett.5c05995
2025
The air-water interfacial nitrogen cycle produces irrigatable-level ammonium nitrateSong X., Basheer C., Xu J., Zare R. N.
Chemical Science
2025
Microdroplet-Driven Synthesis of a Metal-Organic Framework CatalystSong X., Jallow J., Basheer C., Bakdash R. S., Alaliwi A., Alzamil A. A., Zare R. N.
Angewandte Chemie International Edition · DOI 10.1002/anie.202515006
2024
Onsite Ammonia Synthesis from Water Vapor and Nitrogen in the AirSong X. et al.
Science Advances · DOI 10.1126/sciadv.ads4443
2024
Wet-dry cycles cause nucleic acid monomers to polymerize into long chainsSong X., Simonis P., Deamer D., Zare R. N.
Proceedings of the National Academy of Sciences · DOI 10.1073/pnas.2412784121
2024
Oxidation of Ammonia in Water Microdroplets Produces Nitrate and Molecular HydrogenSong X., Basheer C., Xia Y., Zare R. N.
Environmental Science & Technology
2023
Making Ammonia from Nitrogen and Water MicrodropletsSong X., Basheer C., Zare R. N.
Proceedings of the National Academy of Sciences · DOI 10.1073/pnas.2301206120
2023
Water Microdroplets-Initiated Methane OxidationSong X., Basheer C., Zare R. N.
Journal of the American Chemical Society
2023
One-Step Formation of Urea from Carbon Dioxide and Nitrogen Using Water MicrodropletsSong X., Basheer C., Zare R. N.
Journal of the American Chemical Society
2023
Immuno-Desorption Electrospray Ionization Mass Spectrometry Imaging Identifies Functional Macromolecules by Using Microdroplet-Cleavable Mass TagsSong X. et al.
Angewandte Chemie International Edition
2022
Spraying Water Microdroplets Containing 1,2,3-Triazole Converts Carbon Dioxide into Formic AcidSong X., Meng Y., Zare R. N.
Journal of the American Chemical Society · DOI 10.1021/jacs.2c07779
2021
Hydrogen-Deuterium Exchange Desorption Electrospray Ionization Mass Spectrometry Visualizes an Acidic Tumor MicroenvironmentSong X., Zang Q., Zare R. N.
Analytical Chemistry
2020
Oral squamous cell carcinoma diagnosed from saliva metabolic profilingSong X. et al.
Proceedings of the National Academy of Sciences · DOI 10.1073/pnas.2001395117
LAB LIFE
LAB LIFE
结构脂质组实验室环境
4 Photos
Laboratory Environment
Modern laboratory spaces for analytical chemistry, sample preparation, and mass spectrometry-oriented research.
Instrument Area
Shared experimental environment supporting molecular measurement and method development.
Sample Preparation
Clean and organized spaces for daily experiments, method development, and collaborative work.
Lab Lounge
A shared resting area for informal discussion and group communication.
聚餐团建
1 Photos
Group Dinner
Lab life also includes conversations, collaboration, and community beyond the bench.
JOIN OUR LAB
Come build science with us
We welcome students and collaborators interested in mass spectrometry, spatial omics, condensate chemistry, and clinical molecular measurement.
Apply Now